Publications
2009
- Poh, Mee Kian; Yip, Andy; Zhang, Summer; Priestle, John P.; Ma, Ngai Ling; Smit, Jolanda M.; Wilschut, Jan; Shi, Pei-Yong; Wenk, Markus R.; Schul, Wouter. A small molecule fusion inhibitor of dengue virus. Antiviral Research (2009), 84(3), 260-266.
- Yin, Zheng; Chen, Yen-Liang; Schul, Wouter; Wang, Qing-Yin; Gu, Feng; Duraiswamy, Jeyaraj; Reddy Kondreddi, Ravinder; Niyomrattanakit, Pornwaratt; Lakshminarayana, Suresh B.; Goh, Anne; Xu, Hao Ying; Liu, Wei; Liu, Boping; Lim, Joanne Y. H.; Ng, Chuan Young; Qing, Min; Lim, Chin Chin; Yip, Andy; Wang, Gang; Chan, Wai Ling; Tan, Hui Pen; Lin, Kai; Zhang, Bo; Zou, Gang; Bernard, Kristen; Garrett, Christine; Beltz, Karen; Dong, Min; Weaver, Margaret; He, Handan; Pichota, Arkadius; Dartois, Veronique; Keller, Thomas H.; Shi, Pei-Yong. An adenosine nucleoside inhibitor of dengue virus. Proceedings of the National Academy of Sciences of the United States of America, Early Edition (2009), (Nov. 16 2009), 1-5, 5 pp.
- Yin, Zheng; Chen, Yen-Liang; Kondreddi, Ravinder Reddy; Chan, Wai Ling; Wang, Gang; Ng, Ru Hui; Lim, Joanne Y. H.; Lee, Wan Yen; Jeyaraj, Duraiswamy A.; Niyomrattanakit, Pornwaratt; Wen, Daying; Chao, Alex; Glickman, J. Fraser; Voshol, Hans; Mueller, Dieter; Spanka, Carsten; Dressler, Sigmar; Nilar, Shahul; Vasudevan, Subhash G.; Shi, Pei-Yong; Keller, Thomas H.. N-Sulfonylanthranilic Acid Derivatives as Allosteric Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase. Journal of Medicinal Chemistry (2009), 52(24), 7934-7937.
- Barry, Clifton E., III; Boshoff, Helena I.; Dartois, Veronique; Dick, Thomas; Ehrt, Sabine; Flynn, JoAnne; Schnappinger, Dirk; Wilkinson, Robert J.; Young, Douglas. The spectrum of latent tuberculosis: rethinking the biology and intervention strategies. Nature Reviews Microbiology (2009), 7(12), 845-855.
- Bodenreider, Christophe; Beer, David; Keller, Thomas H.; Sonntag, Sebastian; Wen, Daying; Yap, Li Jian; Yau, Yin Hoe; Shochat, Susana Geifman; Huang, Danzhi; Zhou, Ting; Caflisch, Amedeo; Su, Xun-Cheng; Ozawa, Kiyoshi; Otting, Gottfried; Vasudevan, Subhash G.; Lescar, Julien; Lim, Siew Pheng. A fluorescence quenching assay to discriminate between specific and nonspecific inhibitors of dengue virus protease. Analytical Biochemistry (2009),395(2),195-204.
- Su, Xun-Cheng; Ozawa, Kiyoshi; Yagi, Hiromasa; Lim, Siew P.; Wen, Daying; Ekonomiuk, Dariusz; Huang, Danzhi; Keller, Thomas H.; Sonntag, Sebastian; Caflisch, Amedeo; Vasudevan, Subhash G.; Otting, Gottfried. NMR study of complexes between low molecular mass inhibitors and the West Nile virus NS2B-NS3 protease. FEBS Journal (2009), 276(15), 4244-4255.
- Fink, Katja; Ng, Cedrig; Nkenfou, Celine; Vasudevan, Subhash G.; van Rooijen, Nico; Schul, Wouter. Depletion of macrophages in mice results in higher dengue virus titers and highlights the role of macrophages for virus control. European Journal of Immunology (2009), 39(10), 2809-2821.
- Low, Kai Leng; Rao, P. S. Srinivasa; Shui, Guanghou; Bendt, Anne K.; Pethe, Kevin; Dick, Thomas; Wenk, Markus R. Triacylglycerol utilization is required for regrowth of in vitro hypoxic nonreplicating Mycobacterium bovis bacillus Calmette-Guerin. Journal of Bacteriology (2009), 191(16), 5037-5043.
- Wang, Qing-Yin; Patel, Sejal J.; Vangrevelinghe, Eric; Xu, Hao Ying; Rao, Ranga; Jaber, Deana; Schul, Wouter; Gu, Feng; Heudi, Olivier; Ma, Ngai Ling; Poh, Mee Kian; Phong, Wai Yee; Keller, Thomas H.; Jacoby, Edgar; Vasudevan, Subhash G. A small-molecule dengue virus entry inhibitor. Antimicrobial Agents and Chemotherapy (2009), 53(5), 1823-1831.
- Rothwell, Christopher; Le Breton, Aude; Ng, Chuan Young; Lim, Joanne Y. H.; Liu, Wei; Vasudevan, Subhash; Labow, Mark; Gu, Feng; Gaither, L. Alex. Cholesterol biosynthesis modulation regulates dengue viral replication. Virology (2009), 389(1-2), 8-19.
- Schreiber, Mark; Res, Ivica; Matter, Alex. Protein kinases as antibacterial targets. Current Opinion in Cell Biology (2009),
- Rajamanonmani, Ravikumar; Nkenfou, Celine; Clancy, Paula; Yau, Yin Hoe; Shochat, Susana Geifman; Sukupolvi-Petty, Soila; Schul, Wouter; Diamond, Michael S.; Vasudevan, Subhash G.; Lescar, Julien. On a mouse monoclonal antibody that neutralizes all four dengue virus serotypes. Journal of General Virology (2009), 90(4), 799-809.
- Schreiber, Mark J.; Holmes, Edward C.; Ong, Swee Hoe; Soh, Harold S. H.; Liu, Wei; Tanner, Lukas; Aw, Pauline P. K.; Tan, Hwee Cheng; Ng, Lee Ching; Leo, Yee Sin; Low, Jenny G. H.; Ong, Adrian; Ooi, Eng Eong; Vasudevan, Subhash G.; Hibberd, Martin L. Genomic epidemiology of a dengue virus epidemic in urban Singapore. Journal of Virology (2009), 83(9), 4163-4173.
- Ekonomiuk, Dariusz; Su, Xun-Cheng; Ozawa, Kiyoshi; Bodenreider, Christophe; Lim, Siew Pheng; Yin, Zheng; Keller, Thomas H.; Beer, David; Patel, Viral; Otting, Gottfried; Caflisch, Amedeo; Huang, Danzhi. Discovery of a non-peptidic inhibitor of West Nile virus NS3 protease by high-throughput docking. PLoS Neglected Tropical Diseases (2009), 3(1), No pp. given. CODEN: PNTDAM ISSN:1935-2735.
- Kim, Pilho; Kang, Sunhee; Boshoff, Helena I.; Jiricek, Jan; Collins, Margaret; Singh, Ramandeep; Manjunatha, Ujjini H.; Niyomrattanakit, Pornwaratt; Zhang, Liang; Goodwin, Michael; Dick, Thomas; Keller, Thomas H.; Dowd, Cynthia S.; Barry, Clifton E. Structure-Activity Relationships of Antitubercular Nitroimidazoles. 2. Determinants of Aerobic Activity and Quantitative Structure-Activity Relationships. Journal of Medicinal Chemistry (2009), 52(5), 1329-1344.
- Kim, Pilho; Zhang, Liang; Manjunatha, Ujjini H.; Singh, Ramandeep; Patel, Sejal; Jiricek, Jan; Keller, Thomas H.; Boshoff, Helena I.; Barry, Clifton E., III; Dowd, Cynthia S. Structure-Activity Relationships of Antitubercular Nitroimidazoles. 1. Structural Features Associated with Aerobic and Anaerobic Activities of 4- and 5-Nitroimidazoles. Journal of Medicinal Chemistry (2009), 52(5), 1317-1328.
Neglected diseases
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